Sistina is an old style serif typeface designed in 1950 by Hermann Zapf.

Sistina is an all-capitals titling font intended as a heavy supplement to Michelangelo Titling, based on inscriptional capitals in Rome. Sistina was first released in metal in 1951. The recent digital version from Linotype adds small capitals. Hermann Zapf also collaborated with Akira Kobayashi to make a revised version of Sistina named "Palatino Imperial" as part of the Palatino Nova font family.